I took a chance on this truck knowing Ford has had reliability issues in the past. My brief experience with this truck, before I returned for a refund only, reinforced this concern. The truck, an EcoBoost 3.5L V6 version, was experiencing significant Engine Timing Cover Oil Leak at only around 40k miles. Online searches turned up many others complaining of the same problem. Also, take this for what it's worth but online searches of the EcoBoost 3.5L V6 F150 turned up a lot of complaints of sudden loss of power on highway under acceleration as well which I found to be pretty alarming. I will admit I was impressed with the acceleration but I never did get close to the advertised MPG stated by Ford even when I was driving conservatively.
This was a pre-owned company truck with 48,000 miles. As expected it showed some normal signs of wear but also signs of good maintenance. Put fresh tires and shocks, wash and polished - good to go! I use it to pull my small travel trailer and have put about 15,000 miles on it with out a problem. Gas mileage when towing is 13-15 (@65-75mph more often 13), solo 18-20 (not often 20 though). Happy with this truck.
Realistically, I'm not sure I would recommend it. It's neither great nor totally subpar. Just meh. After 6 months of ownership it feels like my previous two trucks (Toyota Tundra and Chevy Avalanche) were a better built vehicles. There is a brake recall regarding the master cylinder that is nearly a year old that Ford does not have a fix for yet. It is easy to tell that Ford is only concerned with getting these trucks manufactured as fast as they can to maintain market share without a huge concern for quality.