Get pre-qualified with
no impact to your credit
Shop with your
personalized terms
Mercedes-Benz
GLS450
2021
Used 2021 Mercedes-Benz GLS450 near me for sale
14 matches
Price drop
2021 Mercedes-Benz GLS450
$45,998*$46,998
41K mi$899 Shipping | Est. arrival 12/12-12/20CarMax Jackson (MS), MS
2021 Mercedes-Benz GLS450
$42,998*
47K mi$999 Shipping | Est. arrival 12/12-12/20CarMax Springfield, MO
Price drop
2021 Mercedes-Benz GLS450
$48,998*$49,998
43K mi$1499 Shipping | Est. arrival 12/12-12/20CarMax Southwest Freeway, TX
Price drop
2021 Mercedes-Benz GLS450
$41,998*$42,998
50K mi$1999 Shipping | Est. arrival 12/18-12/26CarMax Sacramento/Roseville, CA
Reserved
Reserved
Reserved
Reserved
Reserved
Sell us your car
Selling or trading in?
We want your car.
Reserved
Reserved
Reserved
Coming soon
2021 Mercedes-Benz GLS450 customer reviews
Overall rating (based on 2 reviews)
3.0
5 star
1
4 star
0
3 star
0
2 star
0
1 star
1
faulty engine
My Mercedes I bought in 2021 had many issues right from the start. I think it had a faulty engine and I didn’t realize it until it stopped suddenly as I’m driving it on the road. I could’ve been killed if there was moving traffic behind me. So many other issues such as AC/heat does work consistently. Automatic Seats don’t move sometimes, phone charger dock doesn’t work, park gear didn’t work sometimes and many other issues. Mercedes refused to take this car back under the lemon law as it clearly is a lemon! My car was in the shop for months and I lost value on it as they had to replace the engine. No compensation was offered except one month payment which I refused. The car still doesn’t drive well and AC/heat still doesn’t work along with other issues. I feel very wronged by Mercedes.
PROS
Interior Space
CONS
Reliability
engine died as I’m driving and I could’ve been killed
Technology and Entertainment
AC and heat doesn’t work properly
nahla
Jan 30, 2023 A great car with power and features
PROS
Technology and Entertainment
Tech in this car is great! It does what one would expect of a luxury vehicle. However, vehicle customization abilities lag its competitors
Ride and Handling
comfortable seating with an ability to customize the fit. the finish feels like it should with luxurious materials.
Cabin Noise
very quiet ride with very minimal noise for the size and design even at high speeds.
CONS
Dashboard
sometimes the driver’s console takes a bit of time to start. The ability to customize the ride is less than its competitors.
John
Aug 10, 2025 2021 Mercedes-Benz GLS450 FAQs
The 2021 Mercedes-Benz GLS450 offers 20 MPG City and 24 MPG Highway.
It is important to remember factors such as driving style, weather conditions, and the use of features such as Eco mode can impact fuel efficiency.
The Mercedes-Benz GLS450 received a rating of 3.5 out of 5 stars from RepairPal, which RepairPal describes as Above Average. This rating ranks the Mercedes-Benz GLS450 as 4 out of 20 among Luxury Fullsize SUV
The 2021 Mercedes-Benz GLS450 has received an average 3.0 out of 5 stars from our customers. If you're in the market for a 2021 Mercedes-Benz GLS450, check out reviews from customers just like you.
Shop Similar Cars
Research Similar Cars
This price does not include tax, title, and tags. Additional fees may also apply depending on the state of purchase.
*Price excludes tax, title, tags and $699 CarMax processing fee (not required by law). Price assumes that final purchase will be made in the State of VA, unless vehicle is non-transferable. Vehicle subject to prior sale. Applicable transfer fees are due in advance of vehicle delivery and are separate from sales transactions.
† CarMax delivery is available within a 60-mile radius of select stores. Not available to customers in all states. Please contact your nearest store for details.