beebs
Skip to main content

2022 Mercedes-Benz CLS450 review

Research, photos, specs, and expertise

Mercedes-Benz CLS450 highlights

Customer rating

(not yet rated)

RepairPal reliability rating

(data not available)

Mileage (EPA estimate)

22 city, 30 highway, 25 combined

Pricing for current inventory

From $46,998

View our Mercedes-Benz CLS450 inventory
Lighting bolt logo
Can an EV fit my lifestyle? Image of woman on smartphone while charging an EV

Does an EV fit my lifestyle?

On this page

Find your CLS450
then buy online or in-store

Learn more about getting pre-qualified with no impact to your credit score
Price
Year
Mileage
Search our CLS450 inventorySearch for a different car

Shop with your budget in mind

Getting pre-qualified lets you shop with personalized monthly payments, and it doesn't impact your credit score.

Get Pre-qualified

All Mercedes-Benz CLS450 years

What is new for the 2022 Mercedes-Benz CLS450?

  • CLS450 trims have been upgraded with Run Flat Tires and Rear Spoiler as standard equipment this year.

2022 Mercedes-Benz CLS450 trims

Curious how Mercedes-Benz CLS450 trims differ? Use our side-by-side vehicle comparison to see the differences and similarities

Base:

Shop with your budget in mind

Getting pre-qualified lets you shop with personalized monthly payments, and it doesn't impact your credit score.

Get Pre-qualified

Ratings & reliability

Customer ratings

The 2022 Mercedes-Benz CLS450 is not yet rated. Help future customers learn about a car you've owned and write a review.

Mercedes-Benz CLS450 features and specs

Curious how Mercedes-Benz CLS450 trims differ? Use our side-by-side vehicle comparison to see the differences and similarities

4D Sedan 4WD/AWD

Standard Features

  • Air Conditioning
  • Power Mirrors
  • Smart Key
  • Blind Spot Monitor
  • Rear Defroster
  • Power Seat(s)
  • Front Seat Heaters
  • ABS Brakes
  • Sunroof(s)
  • Side Airbags
  • Traction Control
  • Power Locks
  • Overhead Airbags
  • Rear View Camera
  • Memory Seat(s)
  • Cruise Control
  • Power Windows
  • Leather Seats
  • Heated Mirrors
  • Alloy Wheels
  • Run Flat Tires
  • Rear Spoiler
  • Power Hatch/Deck Lid
  • Turbo Charged Engine
  • 4WD/AWD
  • Automatic Transmission
  • Auxiliary Audio Input
  • Navigation System
  • Bluetooth Technology
  • AM/FM Stereo
  • Burmester Audio
  • Apple CarPlay
  • Android Auto

Optional Features

  • Heated Steering Wheel
  • Automated Cruise Control
  • A/C Seat(s)
  • Rear Sunshade
  • Automated Parking
  • Head Up Display
  • Parking Sensors
  • Seat Massagers
  • Lane Departure Warning
  • 20 Inch Plus Wheels
  • Run Flat Tires
  • Satellite Radio Ready

Drive Wheels

All Wheel Drive (4WD/AWD)

Engine size

3.0L

Horsepower

362

Torque (ft-lbs)

369

Engine type

Turbo Gas

Fuel capacity

21.1

Wheelbase

115.7"

Overall length

196.4"

Width

73.9"

Height

56.3"

Leg room

F 41.9"/R 35"

Head room

F 36.9"/R 35.9"

Front tires

P245/40ZR19

Rear tires

P275/35ZR19

Seating capacity

5

Transmission

Automatic

2022 Mercedes-Benz CLS450 FAQ

Here is what's new for the 2022 Mercedes-Benz CLS450:
  • Run Flat Tires
  • Rear Spoiler
The 2022 Mercedes-Benz CLS450 offers the following fuel efficiency options: • Gas: 22 city / 30 highway MPG Actual mileage may vary based on driving conditions, vehicle condition, and driving habits.

Research other vehicles


Price excludes taxes, title, registration, and fees. Applicable transfer fees are due in advance of vehicle delivery and are separate from sales transactions.

We hope you found this information helpful. This content is intended to inform and is not meant to indicate that a particular vehicle is currently available or recommended for you.​

Statements of fuel economy or EV range are based on EPA and other third-party estimates for vehicles when new. Fuel economy and EV range will degrade with time and vary based on age, driving conditions, vehicle history, and other conditions. See fueleconomy.gov for more info.

Unless otherwise noted, information related to featured vehicles comes from third-party sources, including manufacturer information. Product and company names may be trademarks or registered trademarks of third-party entities. Use of them does not imply any affiliation with or endorsement by these entities.​ By clicking on any video links, you will be taken to a third-party site maintained by YouTube, Inc.

We make every effort to provide accurate information, but please verify before purchasing.