2022 Mercedes-Benz CLS450 review
Mercedes-Benz CLS450 highlights
Customer rating
(not yet rated)
RepairPal reliability rating
(data not available)
Mileage (EPA estimate)
22 city, 30 highway, 25 combined
Pricing for current inventory
(no current inventory)
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All Mercedes-Benz CLS450 years
What is new for the 2022 Mercedes-Benz CLS450?
- CLS450 trims have been upgraded with Rear Spoiler and Run Flat Tires as standard equipment this year.
- Running Boards features are now available as options on select trims.
2022 Mercedes-Benz CLS450 trims
Curious how Mercedes-Benz CLS450 trims differ? Use our side-by-side vehicle comparison to see the differences and similaritiesBase:
- 362-hp, 369-lb-ft of torque 3.0L
- Leather Seats
- Memory Seats
- Side Airbags
- Overhead Airbags
- Sunroofs
- Rear Defroster
- Cruise Control
- Power Seats
- View our Mercedes-Benz CLS450 inventory
Shop with your budget in mind
Getting pre-qualified lets you shop with personalized monthly payments, and it doesn't impact your credit score.
Ratings & reliability
Customer ratings
The 2022 Mercedes-Benz CLS450 is not yet rated. Help future customers learn about a car you've owned and write a review.
2022 Mercedes-Benz CLS450 FAQ
The 2022 Mercedes-Benz CLS450 offers 22 MPG City and 30 MPG Highway. It is important to remember factors such as driving style, weather conditions, and the use of features such as Eco mode can impact fuel efficiency.
Here is what's new for the 2022 Mercedes-Benz CLS450:
- Run Flat Tires
- Rear Spoiler
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We hope you found this information helpful. This content is intended to inform and is not meant to indicate that a particular vehicle is currently available or recommended for you.
Statements of fuel economy or EV range are based on EPA and other third-party estimates for vehicles when new. Fuel economy and EV range will degrade with time and vary based on age, driving conditions, vehicle history, and other conditions. See fueleconomy.gov for more info.
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