2022 Lexus IS 350

Research, photos, specs, and expertise

Lexus IS 350 highlights

Customer rating

(not yet rated)

Mileage (EPA estimate)

19 city, 26 highway, 22 combined

Pricing for current inventory

(no current inventory)


All Lexus IS 350 years

What is new for the 2022 Lexus IS 350?

  • IS 350 trims have been upgraded with Rear Spoiler and CD Audio as standard equipment this year.

2022 Lexus IS 350 trims

Curious how Lexus IS 350 trims differ? Use our side-by-side vehicle comparison to see the differences and similarities


  • 311-hp, 280-lb-ft of torque 3.5L
  • Cruise Control
  • Power Seats
  • Heated Steering Wheel
  • Leatherette Seats
  • Rear View Camera
  • Blind Spot Monitor
  • Lane Departure Warning
  • Overhead Airbags
  • View our Lexus IS 350 F-Sport inventory

5 reasons to buy the 2022 Lexus IS 350

1. Great standard trim

You have to check out the "base" trim on the 2022 Lexus IS 350 and you'll find that there is nothing basic about it. The F Sport package is now the standard (and only) trim available and comes with a ton of great equipment. Not only do you get the cool F Sport interior and exterior trim upgrades, but it also comes with standard 19-inch wheels, simulated leather upholstery, dual-zone automatic climate control, and hands-free keyless entry with push-button start, just to name a few.

2. Super sporty

How sporty is the 2022 IS 350? Well, it gets a standard sport-tuned suspension to help make the most of your favorite curvy back road. Plus, the engine is no slouch either. You get a 3.5L V6 putting out a stout 311 horsepower. You can get rear-wheel drive as standard or you can opt for all-wheel drive if you are looking for a bit more foul-weather traction. If you want an even sportier experience, check out the optional F Sport Dynamic Handling package that includes 19-inch BBS® wheels, adaptive suspension dampers, and a limited-slip rear differential.

3. Modern tech

Your next road trip needs the latest technology and integration, and the 2022 IS 350 delivers. You'll get a standard eight-inch touchscreen with Apple CarPlay® and Android Auto smartphone integration to stay connected on the go. If you want more, check out the Navigation package that also gives you a larger 10.3-inch touchscreen display. Naturally, the 2022 IS 350 has a suite of driver aids like forward collision mitigation, lane-keeping assist, blind spot monitoring, and adaptive cruise control.

4. Luxury touches

If you're looking for a comfy luxury sedan, the 2022 IS is a great option. Standard comfort and luxury appointments such as synthetic leather upholstery are joined by great features like rain-sensing windshield wipers, heated exterior mirrors, power-adjustable sport front seats with heating and ventilation, and a heated steering wheel. Check out standalone upgrades like an optional sunroof, a cool power rear sunshade, and even a 17-speaker Mark Levinson® premium audio system.

5. Surprising fuel economy

You'd think that having a great horsepower rating from a 3.5L V6 engine might mean it's not particularly frugal. Interestingly, the 2022 IS 350 performs better than most of its rival compact luxury sedans with six-cylinder engines. You'll find an EPA-estimated 23 mpg combined for the rear-wheel-drive version and an EPA-estimated 22 mpg with all-wheel drive.

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Ratings & reliability

Customer ratings

The 2022 Lexus IS 350 is not yet rated. Help future customers learn about a car you've owned and write a review.


RepairPal gave the Lexus IS 350 an overall reliability rating of 4 out of 5 stars, which RepairPal describes as Excellent. This rating ranks Lexus IS 350 11th out of 68 among Luxury Midsize Cars.

View RepairPal's full rating of the Lexus IS 350

Lexus IS 350 features and specs

F-Sport 2WD 4D Sedan

Standard Features

  • ABS Brakes
  • Air Conditioning
  • Alloy Wheels
  • AM/FM Stereo
  • Android Auto
  • Apple CarPlay
  • Automated Cruise Control
  • Automatic Transmission
  • Auxiliary Audio Input
  • Blind Spot Monitor
  • Bluetooth Technology
  • CD Audio
  • Heated Steering Wheel
  • Lane Departure Warning
  • Leatherette Seats
  • Overhead Airbags
  • Pioneer Sound System
  • Power Locks
  • Power Mirrors
  • Power Seat(s)
  • Power Windows
  • Rear Defroster
  • Rear Spoiler
  • Rear View Camera
  • Satellite Radio Ready
  • Side Airbags
  • Smart Key
  • Traction Control
  • A/C Seat(s)
  • Front Seat Heaters
  • Heated Steering Wheel
  • Mark Levinson Sound
  • Memory Seat(s)
  • Navigation System
  • Parking Sensors
  • Rear Sunshade
  • Sunroof(s)

Drive Wheels

Rear Wheel Drive (2WD)

Engine size




Torque (ft-lbs)


Engine type


Fuel capacity




Overall length






Leg room

F 44.8"/R 32.2"

Head room

F 38.2"/R 36.9"

Front tires


Rear tires


Seating capacity




2022 Lexus IS 350 FAQ

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