2022 Mercedes-Benz S580 review

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Mercedes-Benz S580 highlights

Customer rating

(not yet rated)

RepairPal reliability rating

(data not available)

Mileage (EPA estimate)

16 city, 25 highway, 19 combined

Pricing for current inventory

(no current inventory)


All Mercedes-Benz S580 years

What is new for the 2022 Mercedes-Benz S580?

  • S580 trims have been upgraded with Automated Cruise Control, Seat Massagers, Automated Parking, 20 Inch Plus Wheels, and CD Audio as standard equipment this year.
  • Head Up Display, Rear A/C Seat(s), and Rear Spoiler features are now available as options on select trims.

2022 Mercedes-Benz S580 trims

Curious how Mercedes-Benz S580 trims differ? Use our side-by-side vehicle comparison to see the differences and similarities


  • 496-hp, 516-lb-ft of torque 4.0L
  • Panoramic Sunroof
  • Automated Cruise Control
  • Memory Seats
  • Front Seat Heaters
  • Seat Massagers
  • Overhead Airbags
  • Rear View Camera
  • Automated Parking
  • View our Mercedes-Benz S580 inventory

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Ratings & reliability

Customer ratings

The 2022 Mercedes-Benz S580 is not yet rated. Help future customers learn about a car you've owned and write a review.

Mercedes-Benz S580 features and specs

(no trim) 4WD/AWD 4D Sedan

Standard Features

  • 20 Inch Plus Wheels
  • 4WD/AWD
  • A/C Seat(s)
  • ABS Brakes
  • Adjustable Suspension
  • Air Conditioning
  • Alloy Wheels
  • AM/FM Stereo
  • Android Auto
  • Apple CarPlay
  • Automated Cruise Control
  • Automated Parking
  • Automatic Transmission
  • Blind Spot Monitor
  • Bluetooth Technology
  • Burmester Audio
  • CD Audio
  • Cruise Control
  • Front Seat Heaters
  • Lane Departure Warning
  • Leather Seats
  • Memory Seat(s)
  • Navigation System
  • Overhead Airbags
  • Panoramic Sunroof
  • Parking Sensors
  • Power Hatch/Deck Lid
  • Power Locks
  • Power Mirrors
  • Power Seat(s)
  • Power Windows
  • Rear Defroster
  • Rear Defroster
  • Rear Sunshade
  • Rear View Camera
  • Satellite Radio Ready
  • Seat Massagers
  • Side Airbags
  • Smart Key
  • Traction Control
  • Turbo Charged Engine
  • Burmester Audio
  • Head Up Display
  • Heated Steering Wheel
  • Rear A/C Seat(s)
  • Rear Seat Heaters
  • Rear Spoiler

Drive Wheels

All Wheel Drive (4WD/AWD)

Engine size




Torque (ft-lbs)


Engine type

Turbo Gas

Fuel capacity




Overall length






Leg room

F 41"/R 44"

Head room

F 42.1"/R 39.4"

Front tires


Rear tires


Seating capacity




2022 Mercedes-Benz S580 FAQ

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