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2021 Mercedes-Benz GLS450 review

Research, photos, specs, and expertise

Mercedes-Benz GLS450 highlights

Customer rating

RepairPal reliability rating

Mileage (EPA estimate)

20 city, 24 highway, 21 combined

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All Mercedes-Benz GLS450 years

What is new for the 2021 Mercedes-Benz GLS450?

  • Updated infotainment system with larger touchscreen and improved navigation features
  • Enhanced safety features including adaptive cruise control and lane-keeping assist
  • New engine options available for better fuel efficiency and performance
  • Standard LED headlights for improved visibility and modern appearance

2021 Mercedes-Benz GLS450 trims

Curious how Mercedes-Benz GLS450 trims differ? Use our side-by-side vehicle comparison to see the differences and similarities

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Ratings & reliability

Customer ratings

3 out of 5

2 customer reviews

RepairPal reliability rating

3
1
2
Above Average

RepairPal gave the Mercedes-Benz GLS450 an overall reliability rating of 3.5 out of 5 stars, which RepairPal describes as Above Average. This rating ranks Mercedes-Benz GLS450 5th out of 20 among Luxury Fullsize SUVs.

View RepairPal's full rating of the Mercedes-Benz GLS450

2021 Mercedes-Benz GLS450 FAQ

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* Price excludes taxes, title, registration, and fees. Applicable transfer fees are due in advance of vehicle delivery and are separate from sales transactions.

We hope you found this information helpful. This content is intended to inform and is not meant to indicate that a particular vehicle is currently available or recommended for you.​

Statements of fuel economy or EV range are based on EPA and other third-party estimates for vehicles when new. Fuel economy and EV range will degrade with time and vary based on age, driving conditions, vehicle history, and other conditions. See fueleconomy.gov for more info.

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