Get pre-qualified with
no impact to your credit
Shop with your
personalized terms
Mercedes-Benz
E350
2022
Used 2022 Mercedes-Benz E350 near me for sale
16 matches
2022 Mercedes-Benz E350
$41,998*
25K miFree Shipping | Est. arrival 12/6-12/11CarMax Fredericksburg, VA
2022 Mercedes-Benz E350
$32,998*
60K mi$599 Shipping | Est. arrival 12/12-12/19CarMax Indianapolis, IN
New for you
Price drop
2022 Mercedes-Benz E350
$33,998*$34,998
40K mi$349 Shipping | Est. arrival 12/11-12/19CarMax Town Center, GA
2022 Mercedes-Benz E350
$37,998*
26K mi$699 Shipping | Est. arrival 12/11-12/20CarMax Jacksonville, FL
Price drop
2022 Mercedes-Benz E350
$34,998*$35,998
26K mi$1199 Shipping | Est. arrival 12/13-12/21CarMax McKinney, TX
New for you
Price drop
2022 Mercedes-Benz E350
$38,998*$39,998
12K mi$1999 Shipping | Est. arrival 12/17-12/26CarMax Burbank, CA
Reserved
Sell us your car
Selling or trading in?
We want your car.
Reserved
Reserved
Reserved
Coming soon
Coming soon
Coming soon
Related Articles
2022 Mercedes-Benz E350 customer reviews
Overall rating (based on 1 review)
5.0
5 star
1
4 star
0
3 star
0
2 star
0
1 star
0
Great Car!
PROS
Ride and Handling
Interior Space
Seat Comfort
Tanya
Aug 15, 2025 2022 Mercedes-Benz E350 FAQs
The 2022 Mercedes-Benz E350 offers 22 MPG City and 31 MPG Highway.
It is important to remember factors such as driving style, weather conditions, and the use of features such as Eco mode can impact fuel efficiency.
The Mercedes-Benz E350 received a rating of 3.5 out of 5 stars from RepairPal, which RepairPal describes as Above Average. This rating ranks the Mercedes-Benz E350 as 9 out of 48 among Luxury Fullsize Car
The 2022 Mercedes-Benz E350 has received an average 5.0 out of 5 stars from our customers. If you're in the market for a 2022 Mercedes-Benz E350, check out reviews from customers just like you.
Used Car Value
Shop Similar Cars
Research Similar Cars
This price does not include tax, title, and tags. Additional fees may also apply depending on the state of purchase.
*Price excludes tax, title, tags and $699 CarMax processing fee (not required by law). Price assumes that final purchase will be made in the State of VA, unless vehicle is non-transferable. Vehicle subject to prior sale. Applicable transfer fees are due in advance of vehicle delivery and are separate from sales transactions.
† CarMax delivery is available within a 60-mile radius of select stores. Not available to customers in all states. Please contact your nearest store for details.