2021 Lexus RX 450h review
Lexus RX 450h highlights
Customer rating
RepairPal reliability rating
(data not available)
Pros
- Stylish interior and exterior
- Spacious passenger area
- A quiet and smooth ride
Cons
- Not all that fast acceleration
- Distracting touchpad infotainment interface
- Trunk cargo capacity is smaller than the competition
Mileage (EPA estimate)
29 city, 28 highway, 29 combined
Pricing for current inventory
(no current inventory)
Shop with your budget in mind
Getting pre-qualified lets you shop with personalized monthly payments, and it doesn't impact your credit score.
A luxury hybrid SUV with style and comfort
The 2022 Lexus RX 450h delivers a whisper-quiet experience, even at highway speeds, thanks to excellent materials, a solid interior build, and a hybrid powertrain. Plus, the supportive seats, soft materials, available leather surfaces, and wood accents all elevate the interior look and feel. Powered by a V6 engine and electric motor, the 2021 Lexus RX 450h is a capable SUV with a functional side. Overall, from highway cruising to running errands around town, the 2021 Lexus RX 450h is an ideal luxury SUV with a hybrid twist.
All Lexus RX 450h years
What is new for the 2021 Lexus RX 450h?
- The RX 450h is available in a new trim called the F-SPORT Handling.
- The Performance trim has been discontinued for 2021.
- RX 450h trims have been upgraded with Blind Spot Monitor, Parking Sensors, Panoramic Sunroof, Head Up Display, Mark Levinson Sound, Navigation System, and DVD Video System as standard equipment this year.
- Rear A/C Seat(s) features are now available as options on select trims.
- The L Luxury trim now comes with Rear Seat Heaters as standard equipment.
- The L trim now comes with Cruise Control, Fold-Away Third Row, and Memory Seat(s) as standard equipment.
- The F-Sport trim now comes with Sunroof(s) and Heated Steering Wheel as standard equipment.
- The Base trim now comes with Cruise Control as standard equipment.
2021 Lexus RX 450h trims
Curious how Lexus RX 450h trims differ? Use our side-by-side vehicle comparison to see the differences and similaritiesBase:
- 308-hp, 247-lb-ft of torque 3.5L
- Rear Defroster
- Automated Cruise Control
- Power Seats
- Power Mirrors
- Traction Control
- Leatherette Seats
- Side Airbags
- Overhead Airbags
- View our Lexus RX 450h inventory
L:
- Includes all features available on the Base
- Third Row Seat
- Fold-Away Third Row
- Memory Seats
- Parking Sensors
- Satellite Radio Ready
- View our Lexus RX 450h L inventory
F-Sport:
- Includes all features available on the L
- Sunroofs
- Panoramic Sunroof
- Front Seat Heaters
- Rear Seat Heaters
- A/C Seats
- Heated Steering Wheel
- Head Up Display
- 20 Inch Plus Wheels
- View our Lexus RX 450h F-Sport inventory
F-SPORT Handling:
- Includes all features available on the F-Sport
- Adjustable Suspension
- View our Lexus RX 450h F-SPORT Handling inventory
Luxury:
- Includes all features available on the F-SPORT Handling
- No significant upgrades found on the Luxury
L Luxury:
- Includes all features available on the Luxury
- Rear Sunshade
- Leather Seats
- Power Folding Third Row
- Quad Seats
- View our Lexus RX 450h L Luxury inventory
5 reasons to buy the 2021 Lexus RX 450h
1. Plenty of standard features
From comfort to technology, the 2021 Lexus RX 450h includes the standard features you expect from a luxury SUV. For example, enjoy functional equipment like a power liftgate, dual-zone climate control, and rain-sensing wipers. Plus, there are tech features like Android Auto™ and Apple CarPlay® smartphone integration, an eight-inch touchscreen, and a 4G LTE Wi-Fi hotspot.
Additionally, active driver assists like adaptive cruise control and forward collision mitigation are standard.2. A capable hybrid powertrain
Go further between stops to the gas station in the 2021 Lexus RX 450h. The 2021 Lexus RX 450h gets an EPA-estimated 28 mpg highway and 31 mpg city fuel economy.
Additionally, if you want to do light-duty towing, the 2021 Lexus RX 450h can tow up to an estimated 3,500 pounds when properly equipped.3. Flexible and functional interior
Not just a luxury SUV, the 2021 Lexus RX 450h can adapt to load up the items that everyday life throws at you. That’s because the second-row seats split-fold 40/20/40, which lets you increase the cargo area up to 46.2 cu-ft while flexing the rear seating. Lastly, store small items easily in pockets and cubbies that efficiently use the interior space.
4. Available performance-focused trim
Take your drive to the next level and look for a 2021 Lexus RX 450h with the F Sport package. With adaptive suspension, a lower ride height, and extra drive modes, the F Sport package improves the handling and steering response of the 2021 Lexus RX 450h. The result is a more composed ride that feels more like a sports sedan than an SUV.
5. A quiet and comfortable interior
Enjoy the kind of quiet and smooth ride that exceeds what you’d expect from a luxury SUV in the 2021 Lexus RX 450h. Built using high-end materials, wood accents, and available leather seating, the 2021 Lexus RX 450h delivers comfort that doesn’t fade on prolonged trips. Plus, the reduced road bumps and quieted outside noise combine to create a refined all-around ride.
Shop with your budget in mind
Getting pre-qualified lets you shop with personalized monthly payments, and it doesn't impact your credit score.
Ratings & reliability
Lexus RX 450h features and specs
Curious how Lexus RX 450h trims differ? Use our side-by-side vehicle comparison to see the differences and similarities
L 4WD/AWD 4D Sport Utility
Standard Features
- 4WD/AWD
- ABS Brakes
- Air Conditioning
- Alloy Wheels
- AM/FM Stereo
- Android Auto
- Apple CarPlay
- Automated Cruise Control
- Automatic Transmission
- Auxiliary Audio Input
- Blind Spot Monitor
- Bluetooth Technology
- CD Audio
- Fold-Away Third Row
- Heated Mirrors
- Lane Departure Warning
- Leatherette Seats
- Memory Seat(s)
- Overhead Airbags
- Parking Sensors
- Power Hatch/Deck Lid
- Power Locks
- Power Mirrors
- Power Seat(s)
- Power Windows
- Rear Defroster
- Rear View Camera
- Remote Start
- Satellite Radio Ready
- Side Airbags
- Smart Key
- Third Row Seat
- Traction Control
- 20 Inch Plus Wheels
- A/C Seat(s)
- Blind Spot Monitor
- Front Seat Heaters
- Full Roof Rack
- Head Up Display
- Heated Steering Wheel
- Leather Seats
- Leatherette Seats
- Mark Levinson Sound
- Navigation System
- Panoramic Sunroof
- Rear A/C Seat(s)
- Rear Entertainment System
- Rear Seat Heaters
- Rear Sunshade
- Running Boards
- Sunroof(s)
- Tow Hitch
Drive Wheels
All Wheel (4WD/AWD)
Engine size
3.5L
Horsepower
308
Torque (ft-lbs)
247
Engine type
Hybrid
Fuel capacity
17.2
Wheelbase
109.8"
Overall length
196.9"
Width
74.6"
Height
67.7"
Leg room
F 41.4"/M 30.9"/R 22.6"
Head room
F 39.8"/M 38.5"/R 34.8"
Front tires
P235/65VR18
Rear tires
P235/65VR18
Seating capacity
6
Transmission
Automatic
2021 Lexus RX 450h FAQ
The 2021 Lexus RX 450h is available in multiple trims, each with its own estimated fuel economy, here are the EPA estimates for each trim:
- L: 29 MPG City and 28 MPG Highway
- L Luxury: 29 MPG City and 28 MPG Highway
- Base: 31 MPG City and 28 MPG Highway
- F-Sport: 31 MPG City and 28 MPG Highway
- F-SPORT Handling: 31 MPG City and 28 MPG Highway
Here is what's new for the 2021 Lexus RX 450h:
- F-SPORT Handling
- Blind Spot Monitor
- Parking Sensors
- Panoramic Sunroof
- Head Up Display
Research other vehicles
- lexus rx 450h used car value
- 2010 lexus rx 450h used car value
- 2011 lexus rx 450h used car value
- 2012 lexus rx 450h used car value
- 2013 lexus rx 450h used car value
- 2014 lexus rx 450h used car value
- 2015 lexus rx 450h used car value
- 2016 lexus rx 450h used car value
- 2017 lexus rx 450h used car value
- 2018 lexus rx 450h used car value
- 2019 lexus rx 450h used car value
- 2020 lexus rx 450h used car value
- 2021 lexus rx 450h used car value
- 2022 lexus rx 450h used car value
- Used Lexus RX 450h near me for sale
- Used 2021 Lexus RX 450h near me for sale
- Used 2022 Lexus RX 450h near me for sale
- Used 2020 Lexus RX 450h F-Sport near me for sale
- Used 2022 Lexus RX 450h F-Sport near me for sale
- Used Gray Lexus RX 450h near me for sale
- Used Lexus RX 450h with Heated Steering Wheel near me for sale
- Used 2021 Hybrid Lexus RX 450h near me for sale
- Used Lexus RX 450h L near me for sale
- Used Lexus RX 450h L Luxury near me for sale
- Used 2021 Lexus RX 450h L Luxury near me for sale
- Used Lexus RX 450h with Leather Seats near me for sale
- Used Lexus RX 450h with Memory Seat(s) near me for sale
- Used Lexus RX 450h with Navigation System near me for sale
- Used Lexus RX 450h with Panoramic Sunroof near me for sale
- Used Lexus RX 450h with Remote Start near me for sale
- Used Lexus RX 450h with Sunroof(s) near me for sale
- 2020 Audi S8 review
- 2021 Audi S8 review
- 2022 Audi S8 review
- 2013 BMW M6 review
- 2014 BMW M6 review
- 2015 BMW M6 review
- 2023 Chevrolet Express 2500 review
- 2024 Chevrolet Express 2500 review
- 2012 Chevrolet Express 3500 review
- All things EV
- Used Lexus buying guide
- 2022 Lexus RX 450h review
- 2012 Lexus RX 450h review
- 2014 Lexus RX 450h review
- 2015 Lexus RX 450h review
- 2017 Lexus RX 450h review
- 2018 Lexus RX 450h review
- 2020 Lexus RX 450h review
- Scion tC
- 2025 Subaru BRZ review
We hope you found this information helpful. This content is intended to inform and is not meant to indicate that a particular vehicle is currently available or recommended for you.
Statements of fuel economy or EV range are based on EPA and other third-party estimates for vehicles when new. Fuel economy and EV range will degrade with time and vary based on age, driving conditions, vehicle history, and other conditions. See fueleconomy.gov for more info.
Unless otherwise noted, information related to featured vehicles comes from third-party sources, including manufacturer information. Product and company names may be trademarks or registered trademarks of third-party entities. Use of them does not imply any affiliation with or endorsement by these entities. By clicking on any video links, you will be taken to a third-party site maintained by YouTube, Inc.
We make every effort to provide accurate information, but please verify before purchasing.


